Rheumatology, psychological, disfunctioning "hypothalamic-pituitary-adrenal, HPA

That could endanger the brain systems

The scientists at the University of Aberdeen, which follows the lives of more than 19,000 children, think damaged hormone signals in the brain may play a key role.
Early life experiences can be dangerous bad brain system, causing behavioral problems both in childhood and chronic pain in adulthood wide.

The findings, covering 45 years, which was published in the journal Rheumatology.
All children in this study were born in 1958, and most of the UK.

During the study, until the age of 16 years, parents and teachers assess children's behavior for each "problem" as signs of poor ability to make friends, disobedience, stealing, thumb sucking and nail biting, lying, bullying and truanting.

When the children have grown up and reached the age of 42 they completed a questionnaire asking about psychological pressure. At the age of 45 they completed one another about the pain.
The researchers found that children with severe behavioral problems has doubled the risk of chronic widespread pain.

Dr Dong Pang, principal author of the work and a researcher at the University of Aberdeen, said: "We already know that severe adverse effects in childhood such as inpatient care after road traffic accidents and separation from the mother associated with chronic widespread pain in the adults.
However, until now, it is not known whether maladjusted behavior in children is a long-term marker for this type of pain.

The researchers say that it is not only widespread chronic pain associated with bad behavior in childhood.
Another adult problems associated with behavior problems of childhood include long-term psychiatric problems like depression, anxiety and substance abuse.

They say that all these problems may result from the chain of events set in motion by disfunctioning "hypothalamic-pituitary-adrenal or HPA axis - the system in the brain that control hormones to help regulate body's response to stressful situations.
If further research proves this to be the case, it is possible to intervene early in life to prevent this problem occurs later.

Professor Gary Macfarlane, who also worked on the study, said that lifestyle changes can help change the patterns, including increasing the amount of exercise a person takes, and oversees the signs of psychological stress and behavioral problems in childhood.

Dr John McBeth, a pain expert at Manchester University, said: "While the factors associated with the development of chronic pain which is slowly revealed widespread, it became clear that the events that occurred in early childhood is important.
He said the next challenge is to determine whether the problem with the stress response system operates on the children.