Uptake by Organs, Network, and cell metabolism

In cell metabolism
Pesticide chemicals exposed to the enzymes by changes in the body through a process known as metabolism. Metabolism refers to chemical reactions that change the structure and physiochemical properties of the pesticide to add, delete, or replacement of various chemical components.

Metabolism takes place mainly in the liver, where the cells usually change the original pesticide molecules that are less toxic, more water soluble form that makes it easier to remove the chemical. However, some molecules will be converted to more toxic forms.

Blood is the medium through which pesticides are transported to the organs, the network, and cells. Uptake by cells depends on the physical and chemical properties of pesticides and type of cells involved. Therefore, various pesticide can be distributed to the various networks in the body. Pesticides can enter the network passively by simple diffusion, that is, the pesticide can move from a high concentration in the blood to the lower concentration in body tissue. On pesticides can be transported by a reaction that uses energy to "pull" to the chemicals in the cells.

Elimination of sewage and from the
Metabolized chemicals in the body are eliminated by the kidneys, urine, or brought to the bile in the intestine of the heart. Pesticides may be reabsorbed into the blood system of the gut or excreted in fecal material. Pesticides can also be removed through the end of the lungs or air in the body secretions such as tears, saliva, and susu.

Pesticide storage sites in the
Pesticides May accumulate in body cells, protein, fat, and bone. Is fat-soluble pesticides, especially, that are stored in the body for long periods of time. The depletion of fat the body can release them into the blood.

Absorption of pesticides, MovementWithin, intestines

MovementWithin the blood
The transportation of pesticides in the body depending on whether the pesticide is absorbed through the skin, lungs, or GI tract. Pesticides absorbed in the GI tract to enter the blood stream flows directly to the heart of a major site of metabolism-pesticide dirobohkan immediately after absorption.

People are absorbed into the blood through the skin or through inhalation to the lungs circulating throughout the body before reaching the heart akan dirobohkan. Therefore, the same doses of pesticides may be through inhalation of toxic ingestion.

Skin is a natural barrier to many pesticides, but penetration can occur, especially if the skin is interrupted by cuts and abrasions. From each region gastrointestinal (GI) tract, mouth, esophagus, stomach, small and large intestines, colon, rectum, and internal environment that will dramatically affect the absorption of pesticides. Some of the compounds easily absorbed in the mouth, while others only in the intestines absorb. Some pesticides only pass through the organism (human or animal) without completely absorbed. Pesticides inhaled into the lungs need only to cross the thin barrier separating the lung tissue from the blood supply to get quick access to the blood.

Pesticides can enter the human body through the skin (dermal exposure), mouth (oral exposure), and lungs (inhalation exposure). Sites affected by the level of pesticide absorption into the blood, and the pattern of distribution.

An example of interaction of pesticides in the subcellular level

Ability explained by Target Organ / System Effect
Toxicological effects are often described according to the organ or system that they impact: cardiovascular, respiratory, gastrointestinal, urinary, muscle, frame, and the effect of milling with the skin, peripheral or central nervous system and sense organ effects, immune system effects; effect gland gland endokrin and reproductive system effects. Effect of organs in experimental animals are often, though not always, input is expected from the effects of human exposure to pesticides are the same.

A toxicological insult to one organ may have direct consequences on other parts of the same system, or on some systems, because of the complex interaction and coordination of various body systems.

• enzymes

is a protein that accelerate chemical reactions of specific molecules. A pesticide that interferes with the enzymatic process can prevent, slow or speed up a chemical reaction in cells. Enzymatic disruption can lead to toxic response by the cells, networks, organ, or system. For example, acetylcholinesterase is an enzyme important for nervous system function properly, can be inhibited by organophosphorous insecticides, leading to a nervous system poison.

• Critical component provider

Critical cellular components (eg, DNA, hormone receptors, the energy that produces chemicals, chemical impulsetransmitting nerve, and cell membrane transport protein) can interact with pesticides to produce harmful effects. Pesticides may be molecules that serve a particular purpose. For example: hemoglobin molecule is a special primary function is to transport oxygen in red blood cells. Interference with the hemoglobin so it can not work effectively due to injuries stemming from the changes in oxygen transport.

Toxicity characterized by Effect
Toxicity often can be explained according to the visible or measurable effect is caused.

• Death

is the most toxic effect, occurs when the essential functions of the body changed or inhibited.

• Irritation

Irritation is observed when the pesticides affect the cells of the skin or eyes; corrosion occurs when the integrity of the outside layer of damaged cells. Effect is often referred to as the "burn." Less severe irritation may appear as redness, swelling, or inflammation on the skin. Irritation / corrosion can result from a single or cumulative exposure.

• Skin sensitization

Skin sensitization is an allergic reaction; sensitization require multiple exposures over a period of time. Early exposure "sensitizes" the person, and then the exposure of individuals to react to the chemicals by the "rash." Poison ivy is a familiar example of sensitive skin, natural chemicals.

• Mutagenicity (also called genotoxicity) result from changes in the genetic material of cells. There are two general types: a gene mutation that changes the DNA genetic code and structural mutation that caused chromosome structural damage.


• Mutagenic
Mutagenic compound produces chromosomal aberrations in May by modifying the physical structure or the number of chromosomes, the result for the chromosomes or mismatched, or chromosomes that failed to undergo cell division. Gene mutations, including deletion, addition, or substitution of the chemical components of DNA, which contains all the code information that allows organisms to function. Interference in the genes or chromosomes can lead to disease (including cancer) and birth defects. A mutagen is a concern if the damage to sperm or egg cells, so that the disability must be submitted to successive generations.

• Tumors

Tumors also called neoplasms-a network that is abnormal growths, they can be either benign or malignant. Tumors most friendly because it does not threaten the living cell division is usually slow and the noninvasive cell: They will not spread to the surrounding network. Malignant Tumors rapid share, in the uncontrolled fashion, and spread to cells other body; this, combined with their tendency to withhold nutrition needed by the network healthy, so he destroys, renders them lifethreatening. Tumors are probably one of the four types of cancer:

• Leukemias

Leukemia: the cancer cells from blood red, some white blood cells, and cells that produce these cells.

• Lymphomas

Lymphomas are cancers that affect the organs of the system is weak, such as the lymph nodes.


• Sarcomas

Sarcomas are cancers of connective tissues such as bone, muscle, and cartilage.


• Carcinomas

Carcinomas are cancers of the internal and external epithelial cells.

Toxic pesticides and toxic characteristics described

Virulence characteristics as reversible or irreversible
Toxicity of pesticides that are described as reversible if the impact down or lost when the exposure ended. But in a situation where the pesticidal Adverse effects persist even when exposure is eliminated, which is considered toxic irreversible.

For many pesticides, the response to acute exposure to very different responses to the subchronic or chronic exposure, ie, doses that once administrative May cause little or no response, while some of the exposure (at the same dose) through the intermediate or long period of time may akan produce a significant response.



A pesticide told Adverse effects acutely toxic if one results from the exposure, usually at a relatively high dose. But it should be noted that exposure of the same or lower dose several times within a very short period of time (eg 24 hours) also termed acute. Acute effects in humans is often due to accidents, such as a child ingesting the pesticide. Attempt suicide, and in some cases, the abuse of pesticides roisterous products, may be the acute exposure.
Effect of pesticides vary with the duration of exposure:
• acute (short-term exposure, exposure of one or more of exposure in a very short period of time)
• subchronic (intermediate-term exposure, repeated exposure for a longer period of time)
• chronic (long-term exposure, repeated exposure over a long time)

The toxic effects of some pesticides are reversible when exposure is eliminated, regardless of the dose, while the effects may be reversible on exposure lowdose irreversible but at high doses. Toxic effects that are sometimes reversible, at first, but with the exposure continues to be irreversible, even though the dose.
Whenever the cause of pesticides Adverse effects following acute exposure, it is said to exhibit acute toxicity.



Subchronic toxic effects evident after repeated often (eg, daily) exposure, over weeks or months, to doses of pesticides that may be only little or no response to a single, acute exposure. Body may not eliminate exposure to pesticides before a row, so that resulted in a buildup that trigger subchronic Adverse effects.

Effects due to chronic exposure continues for long period of time-a lifetime, for example. Pesticides can have a cumulative effect on the body, even on a low dose so that no direct or short-term effect is evident. Although it may be the body can recover from the effects of at least one dose or multiple low doses can cause, may not be able to totally between repeated exposure over long period of time. The buildup of chemicals in the host system eventually became known as the chronic effects, and the resulting, cumulative damage can be permanent.

Composition 'C-2'

Composition 'C-2' to make it more difficult than the 'C-4' and Toxic handle. He is also not stable in storage and poor is the right choice for home explosive. It also has a speed lower than the detonation good 'C-4' or 'C-3'. Composition C-2 and C-3
This is highly undesirable because each has a certain nature, and they do not produce as much power as' C 'and' C-4 'compounds.

This is not recommended you make a second type of plastique, this part was written for imformatative only.


'C-3' was developed to eliminate the desired aspects of the 'C-2'.
He was the standard adopted by the military and the composition as follows:
R.D.X. ............... 77%
Mononitrotolulene .... 16%
Dinitrotolulene ...... 5%
Tetryl ............... 1%
T.N.T. guncotton ..... 1%

'C-3' is produced by mixing plastisizing agent in the steam jacketed melting kettle equipped with mechanical stirring attachment. Hot water boiler to the 90-100 degrees centigrade and the stirrer is activated. Water wet R.D.X. akan plastisizing added to the agent and
stirring was continued until the mixture is uniform and all water was driven off. Removing a heat source but continue to stir until the mixture has cooled to room temperature.
It is produced in a steam jacketed (heated) melting pot kettle using the same procedure used in incorporation of 'C-3'. Its composition is as follows:
R.D.X. .................. 80%
Mononitrotolulene ....... 5%
Dinitrotolulene ......... 5%
T.N.T. guncotton ........ 5%
Dimethylformide ......... 5%
(see below for rest of recipe)
Will be taking from the detonation # 6 blasting cap but the use of a booster is always suggested. This explosive has a great explosion effects and is available in standard demolition blocks. Its detonation velocity of 7,700 MPS.
This explosive is as sensitive to impact as TNT Storage at 65 degrees centigrade for four weeks in the relative humidity of 95% does not disrupt the explosive properties.

'C-3' is 133% as well as the explosive TNT A big disappointment from the 'C-3' is the exhilaration that caused it to lose 1.2% of the weight of the blasting explosive properties although not affected.
Water does not affect explosives preformance. So very good for the bottom of the water discharge and will be using a good choice for such applications.

Explosive has adopted this standard

Explosive has adopted this standard and the composition as follows:
R.D.X. ......................... 88.3%
Heavy mineral oil .............. 11.1%
Lecithin ....................... 00.6%
(all percentages are by weight)
All the type 'C' plastic explosives (which include C-2, C-3 and C-4) which is very strong and should be used with utmost caution.

Explosive is only a copy of the British explosives have been taken at the beginning of WWII. This is the choice explosive materials of the type 'C' because the compounds are relatively easy to manufacture and ease of acquisition of plastizer complex. This explosive was available in
standard demolition blocks.

Also plastic 0-40 degrees centigrade. Above 40 degrees the explosive undergoes extrudation become swollen and even explosive properties go relatively unimpaired. Below 0 degrees centigrade to become brittle and cap sensitivity is reduced.
In this composition, the lecithin acts to prevent the formation of large crystals of RDX which would increase the sensitivity of explosive materials. This has a lot of explosive power and relatively not toxic (unless ingested)
Both methods are simple kneading the complex plastisizing to RDX until mixture is uniform. This explosive should be stored in cool, dry place. If properly made the plastique must be very stable in storage even if stored on temparatures elevated for long periods of time.
Explosive manufacturing can be done two ways. The first is to destroy 11.7% plastisizing in unleaded gasoline and mixing with the RDX and allowing gasoline to evaporate until the mixture is free of all gasoline.



Must close very sensitive. A booster will be a good choice, especially if used below 0 degrees centigrade. Detonates at this speed 7900/MPS

Acrylic Plastic Waste

This also further produce toxic fumes.
New legislation requires that the polymerization process conducted in a closed environment, and that steam cleaned, captured, or neutralized before discharge into the atmosphere.
Acrylic plastics manufacturing involves a highly toxic material carefully need storage, handling and disposal.
Polymerization process that can cause an explosion if not monitored correctly.



In a place, acrylic plastic, such as other plastics, not easily biodegradable.
Acrylic plastic is very flammable and must be protected from sources of ignition.
Acrylic plastic is not easily recyclable. This is considered a group 7 plastic among recycled plastics and is not collected for recycling in most communities.
Large pieces can be reformed into other useful objects if they are not suffering too much stress, crazing, or cracking, but this accounts for only a very small portion of the acrylic plastic waste.

Some Diseases Cancer, Pregnancy

Cancer Laboratory tests showed ether in May have the potential to cause cancer, but whether it produces the substance of animals is not known.

Pregnancy.
Drugs have caused congenital malformations and fetal death in chicken embryos in the experiment, but the impact on humans is not clear. Women's exposure to the industry that is more likely to suffer spontaneous abortion. Ether passes from pregnant women to the fetus, but not exposed to chronic and acute medical exposures known to cause birth defects.



Care baby seems unharmed by susu of women using ether. Additional information. "Petroleum ether" ether and medicine is a different matter.

Additional scientific information can be found at:
Connell, K.H. "Drinking in Ulster ether." Quarterly Journal Studies on Alcohol 26 (1965): 629-53.



Nagle, D.R. "Anesthetic Addiction and intoxication: A Historical and Contemporary Survey." International Journal of Addictions 3 (1968): 25-39.

Strickland, R.A. "Ether drinking in Ireland." Mayo Clinic Proceedings 71 (1996): 1015.

Drawbacks It is the stimulation Lighters

Drawbacks


Lighter doses that stimulate breathing, but larger doses depress it. Gas irritates airways. In the high-dose pulse rate and blood pressure decrease.
A serious effect is not desired can be a fatal convulsion. Using ether as a drink that can cause headaches, increase salivation, which is the road from the mouth to the stomach (which lead to vomiting), flatulence and weight. In the form of a liquid substance can disrupt the skin and can be absorbed through it.

Ether is very flammable, and various government regulations to reduce the use of medical opportunity ignition.
Even in the regulations that control the type of clothing worn by the nurse and the type of linen used in the cart, so that static electricity creates a spark explosion. Ether vapor is heavier than air and can accumulate in depressions such as pillows in the field around the patient, so that ignition all over the disaster.
Stories are told from the ether drinkers who died when lighting a pipe or tobacco while indulging too close to the open fire.

Even releasing ether fumes from the mouth to the stove lit is seen as a danger to avoid ignition ether do not flash back and someone down the throat.

It factors.
Some accounts describe the use of ether as potentially addictive.

Drug interactions.
Not enough scientific information to report.

Ether Chemical substance To Drink

The effects of drinking that is almost similar to that produced by the Alcohol, but faster and last appeared briefly.
Encouraging people are confused, may experience feelings of euphoria and hallucinations, may have difficulty walking, and sometimes faint.
Gas is a format that is used recreationally (sometimes together with the drug), but drinking fluid ether is a more general recreational use.
Ether drinking is associated with Ireland, where the custom was adopted in response to limit the alcohol temperance movement in the 1800s. Ether drinking is well known in European countries other also, and the United States.
In the United States in 1800-the sky has been drunk on occasions ranging from a professional medical society meetings to wedding
and quilting bees. Wide variety of shows such as receiving social practice.

Considered less harmful substance than alcohol.
When using ether, nineteenth-century author and physician Oliver Wendell Holmes to make a note of spiritual insight was that he had opened to him with the help of drugs, but then he found a note should be clear.

Substance is not used until the ninth century teens

Substance has been available for hundreds of years it is not used as a medicine until the ninth century teens.

Relaxes the muscle complex, increasing the blood sugar level. Decade is the standard kematirasaan.
Has been superseded by the chemicals work faster, better (the patient), which is less danger of fire.
Knowledgeable medical personnel can use the ether, without a secure complex equipment, drugs are still common in high-tech medical facilities that are not public or nonexistent.
Liquid form of the ether used to wash the medical surface of the skin before putting on the adhesive tape and used to help release the adhesive tape.

Substances cause damage to kidneys

Freon may produce lung spasms. The substance has caused high blood pressure, perhaps as a consequence of kidney damage resulting from the substance. Users have described accelerated heartbeat. Inhalation has also brought on a cardiac emergency called ventricular fibrillation, which is fatal without immediate medical intervention. Even if the person survives, most individuals do not receive sufficient help in time to prevent lasting brain injury from lack of oxygen. In one case a 15-year-old freon user not only experienced the heart emergency but suffered lung and muscle damage as well. Using enough freon in a closed space can be fatal due to oxygen starvation.
Abuse factors.
Not enough scientific information to report about tolerance, dependence, withdrawal, or addiction.

Drug interactions.
Not enough scientific information to report.

Cancer.
Not enough scientific information to report.
Inhalers have also reported injuries ranging from lacerations to a broken neck when they lost consciousness and collapsed while sniffing freon; such harm may not be attributable to the substance itself but can be a consequence of using it.
Maxwell, J.C. “Deaths Related to the Inhalation of Volatile Substances in Texas: 1988–
1998.” American Journal of Drug and Alcohol Abuse 27 (2001): 689–97.

Wegener, E.E., K.R. Barraza, and S.K. Das. “Severe Frostbite Caused by Freon Gas.”
Southern Medical Journal 84 (1991): 1143–46.
Pressurized freon gas can be cold enough to cause frostbite. Case reports note cold damage to fingers, along with drooling caused by frostbite injury to lips, tongue, and inside of the mouth. One report described “notable deformation” of someone’s face; in another case, plastic surgery was necessary to reconstruct the damaged face of one recreational user.

Injection of freon is possible but seems to occur as industrial accidents to fingers rather than as an effort to obtain psychological effects. Upon injection, the gas, which has been under pressure in a container, is free to expand inside the body, producing uncomfortable results. Case reports indicate that victims fully recover.

Goldsmith, R.J. “Death by Freon.” Journal of Clinical Psychiatry 50 (1989): 36–37.
Additional scientific information may be found in:
“Aerosols for Colds.” Medical Letter on Drugs and Therapeutics 15 (1973): 86–88.

Brady, W.J., Jr., et al. “Freon Inhalational Abuse Presenting with Ventricular Fibrillation.”
American Journal of Emergency Medicine 12 (1994): 533–36.

Lee, T., et al. “Oral Frostbite Secondary to Freon Propellant Abuse.” Journal of Toxicology.
Clinical Toxicology 34 (1996): 562.
Injury has also occurred from exposure to liquid freon, which is extremely cold and can cause severe frostbite. In one case, portions of a stomach died from freezing, causing holes that had to be surgically repaired. As with injections, injuries from liquid freon seem to be industrial accidents rather than results of recreational use.

Pregnancy.
Not enough scientific information to report.

Then Click Here

True ... Once a drug Interaction Not enough scientific information to report it

Cancer
There are various types of DNA damage to cancer-causing potential, and evidence of DNA damage was detected in working with people affected by petrol fumes. A large study reviewed the medical record 19,000 car service station attendants through the 20-year higherthan-usual number of cancer found in the nose, throat, lungs and kidneys. Steam gas suspected of causing acute myeloid leukemia. Gasoline fumes cause cancer in experimental animals.

Pregnancy.
Baby born women recreational gasoline May inhalers during pregnancy exhibition of muscle tension, head deformities, mental delays, and lack of other, leading some researchers to suspect that the gas causes birth defects.

Kith, E.J., F. and A. Lingl. "Model psychosis' Produced by inhalation of vapor Gasoline." American Journal of Psychiatry 120 (1964): 757-761.
Additional scientific information can be found at:
Beckmann, G., and G. Hauck. "Tod durch 'suicide' Benzindampfe oder? [Death due to 'self' or steam Gasoline?]" Archiv fu ¨ r Kriminologie 154 (1974): 77-82.

Edminster, S.C., and M. J. Bayer. "Recreational Gasoline Sniffing: Gasoline acute intoxication
and latent Organolead poisoning. Case reports and literature. "Journal of Emergency Medicine 3 (1985): 365-70.
Seshia, S.S., et al. "The Neurological manifestations of chronic inhalation of Leaded Gasoline." Development Medicine and Child Neurology 20 (1978): 323-34.
Valpey, R., et al. "Acute and chronic progressive Encephalopathy Due to Gasoline
Sniffing. "Neurology 28 (1978): 507-10. Maruff, P., et al." Neurological and Cognitive Abnormalities Associated with Chronic Petrol Sniffing. "Brain 121 (1998): 1903-17.
Poklis, A., and C.D. Burkett. "Gasoline Sniffing: A Review." Clinical toxicology 11 (1977): 35-41.
Nurcombe, B., et al. "A Hunger for Stimuli: The Psychosocial History of Petrol inhalation." British Journal of Medical Psychology 43 (1970): 367-74.

For more details View Here

Klinis toksikologi 19 (1982): 493-99

Cautioned nurses are taking steps to avoid the accumulation of fumes if tce in the incubators used to remove adhesive tape from a baby. Nonprescription cold aerosol tce have a solution as the solution components, and death has been given to the tce in their products. Tce recreational use is intended to produce feelings of euphoria. Depending on the amount of inhalation, tce can make the mouse more active or less active. Substance in humans tend to excite the people first, and then make them lazy.

Pointer, J. "Correction Fluid type inhalation: A New Substance of It." Journal
of toxicology: Clinical toxicology 19 (1982): 493-99.
Typical cases that require medical assistance involving patients who are stimulated they start running vigorously until they collapse. Dose of the drug in May produce dizziness and difficulty in moving arms and legs.
"1,1,1-Trichloroethane." IARC Monographs on the Evaluation Risks to Human carcinogenic,
pt.2, 71 (1999): 881-903.
Inhaling low levels tce can disrupt the person's nose, and the higher amount it would be worse. Steam can cause the springs. Although the steam experiment exposing volunteers to show little or no effect on Adverse some tests of mental acuity (and even in some of the steps repair, depending on the dose), the industry is exposed to the fumes have become angry and moody, indicating they had difficulty maintaining balance, and display problems with concentration and short-term memory. Pain, tingling, or other sensory disabilities can occur, such as headache, nausea, and low blood pressure. Brain, heart, kidneys, lungs, and heart disease have been observed.

Respiratory arrest, such as stroke and coma. Fatal heart rhythm changes may occur. Heart attack can result from overdose, but the extraordinary. Case report tells of chronic exposure causes fatal damage to the blood, skin, and internal organs. Autopsy revealed other examples in the heart, kidneys, lungs, and damage to a teenager who died of overdose tce.
King, G.S., J. E. Smialek, and W. G. Troutman. "Sudden Death in young people so that
from the inhalation of typewriter correction Fluid. "Journal of the American Medical
Association 253 (1985): 1604-6.
In addition to sniffing, chemicals can also be absorbed through the skin, the danger to the person who is touched by the liquid.

Kelafant, G.A., R.A. Berg, and R. Schleenbaker. "Toxic Encephalopathy Due to 1,1,1 --
Trichloroethane Exposure. "American Journal of Industrial Medicine 25 (1994):
439-46.
Tce liquid will not burn, the substance is often regarded as nonflammable. Steam will be burned, however. Tce is used to clean the interior space shuttle booster casings solid fuel to relaunch, and a worker who died during the steam cleaning facility tce ignited.

D'Costa, D.F., and N.P. Gunasekera. "Following Fatal Cerebral edema Trichloroethane
It. "Journal of the Royal Society of Medicine 83 (1990): 533-34.
It factors.
Tolerance was reported. Dependence can develop in the mouse.

Withdrawal symptoms in mice can be reduced by dosing them with alcohol, pentobarbital, or midazolam. Such as cross-tolerance indicates that operate as tce depressant, and people have experienced the depressant action thereof.

Additional scientific information can be found at:
"Aerosols for Colds." Medical Letter Drugs and therapy in 15 (1973): 86-88.
Drug interactions.
In animal experiments tce cause fatal heart rhythm problems that are worsened by alcohol.

Cancer.
Laboratory tests showed tce can cause cancer, but the combination of the ability to produce human and animal diseases that are not clear.
Additional information. Scientific writings sometimes use the abbreviation
"Tce" to trichloroethylene, also called trichlorethylene (CAS RN 79-01-6).
Complex and 1,1,1-trichloroethane are sometimes found in one
products, but they are different chemicals. Trichloroethylene is not considered
a substance abuse.
Pregnancy.
Industrial relations suspected cause fetal abnormality and spontaneous abortion. One group of experimenters found that chronic fetal exposure because of the rat heart defect, but the other groups of researchers found no effect. Animals other work has been produced birth defects involving the bone. In mice, fetal exposure simulation experiment recreational abuse pattern
cause of low birth weight with the slow maturation of the brain and behavior of children.

Description More Click Here

Tetrabromoethane Safety Data Sheet

Fighting Suitable extinguishing

Special Risk:
Development of combustion gas vapours may be hazardous in the event of fire. Develop activities in the fire: hydrogen bromide.

Fire fighting equipment:
Try not to stay in the danger zone without self-breathing. How to avoid contact with skin, safe distance, and wear suitable protective clothing and helmets.

Other information:
Vapours out with water. Prevent the entry of fire-water or surface water.

Release action:
People associated with the prevention measures:
Menjahui substance contact. Not the vapours / aerosols. Stock Ensure fresh air in a closed space.

How to environmental protection:
Try not to let dirt enter the system.

The process of how to cleaning / absorption:
Make or take-absorbent material with a liquid (eg Chemizorb (C)). For disposal. Must clean the area already affected.

Handling and storage
Handling:
Working under the tent. Should not inhale substance. Avoid generation of vapours / aerosols.

Storage:
Tightly closed in well-ventilated place. Accesible only allowed to people. At 15 ° C
to 25 ° C.

Exposure controls / personal protection
Personal protection equipment:
Protective clothing should be selected specifically for the workplace, depending on the concentration and quantity of the hazardous substances handled.
Respiratory protection:
required when vapours / aerosols produced. Filter A (acc. to DIN 3181) for vapours of organic compounds.

Hand protection:
Full contact:
Glove material: viton
Layer thickness: 0.70 mm
Breakthrough time:> 480 Min.

In splash contact:
Glove material: butyl rubber
Layer thickness: 0.7 mm
Breakthrough time:> 30 Min.

Protective gloves should be used in accordance with the specifications of EC directive 89/686/EEC and the EN374 standard, for example, KCl 890 Vitoject (C) (full contact), 898 Butoject (C) (splash contact). Breakthrough times stated above were determined by laboratory tests in KCl Acc. to EN374 with samples of the type of gloves is recommended.

Industrial hygiene:
Immediately change contaminated clothing. Apply skin-protective barrier cream. Wash hands and face after working with substance. Under no circumstances eat or drink in the workplace. Working under the tent. Do not inhale substance.

Physical and chemical properties
Forms: liquid
Color: red
Prestige: slightly sweet, spicy
pH value is not available
Melting point -1 ° C
Boiling point 239 ° C (decomposition)
Ignition temperature 335 ° C
Flash point not available
Lower explosion limit is not available
up is not available
Water vapor pressure (20 ° C) 0,03-0,13 PPA
Relative vapor density 11.92
Density (25 ° C) 2.96 g/cm3
Solubility in
water (20 ° C) 0.63 g / l
ethanol (20 ° C) soluble
Thermal decomposition 239-242 ° C
Bioconcentration factors 0,5-7,0

Stability and reactivity
Conditions to be avoided Heating. (Release from: hydrogen bromide). Materials to be avoided Violent reactions can be done with: / Risk of explosion with: alkali metals, alkaline earth metals, metals in the form of powder, sodium amide. Hazardous decomposition products in the event of fire.

More information
heat-sensitive, light-sensitive, contrary to various metals (iron, zinc, metal lighter), various plastics, rubber.

Toxicological information
3 acute toxicity
LC50 (inhalation, rat): 550 mg / m / 4 h.
LD50 (dermal, rat): 5250 mg / kg.
LD50 (oral, rat): 1200 mg / kg.

Literature to our data does not match the label specified by the European Commission. EC has dossiers which have not been published.

Subacute to chronic toxicity
Bacterial mutagenicity:
Ames test: positive.

Further toxicological information
After inhalation:
Irritations of the mucous membranes, cough, and dyspnea.

After skin contact:
Little irritations. Danger of skin absorption.

After eye contact:
Irritations.

After swallowing:
irritations of mucous membranes in the mouth, pharynx, esophagus and gastrointestinal tract.

Systemic effects:
Nausea, vomiting, headache.

After absorption of toxic quantities:
narcosis, coma, respiratory paralysis.

Effect / Damage:
liver, kidney.

Ecological information
Biological degradation:
Biodegradation: 29.0% / 14 d.
Biologically not easily degradable.
Behavior in environmental compartments:
Distribution: log p (o / w): 280.
Appreciable bioaccumulation potential that should be expected (log P (o / w)> 3).

Ecotoxic effects:
Biological effects:
Harmfull against the organism.

Description More Click Here

Some of the Materials Chemistry

Some Material
Synonym: Acid Red 97, [1.1 '-Biphenyl] -2.2'-disulfonicacid, 4.4 '-bis [(2-hydroxy-1-naphthalenyl) azo] -, disodiumsalt, acid red anthracene GA-CF , red chrome alizarine G, GM airedale scarlet, scarlet altochrome G, amacid a scarlet G, G anthra in red, a red azo G, GS benzyl red, red belacid appellative G, CI 22890, a GP coomassie scarlet, scarlet fast cyanine GR , naphthalene red leather G, optanol scarlet R, G pharmaglo red, red polycor GS, GS supranol scarlet, red tetracid AGE, is widely used:
Molecular formula: C32H22N4O8S2Na2
CAS No: 10169-02-5
EINECS No: 233-439-3

Physical
Visible: solid
Melting point:
Boiling point:
Vapor density:
Pressure:
Density (g cm-3):
Flash point:
Explosion limits:
Autoignition temperature:
Water solubility:

Stability
Stable. Opposite with strong oxidizing agents.

Toxicology
Danger or something with the act - not all toxicology investigated.

Risk phrases

Transportation information
Non-hazardous for air, sea and road freight.